Harnessing Cannabis sativa Oil for Enhanced Skin Wound Healing
30 September, 2024
A scientific review says cannabis oil may help promote the healing of skin wounds, finding that it offers promising benefits. The review looked specifically at how cannabis oil can reduce so-called “reactive oxygen species” (ROS) during the healing of wounds. Those chemicals play a crucial role in wound development by causing cell and tissue damage.
“Increased ROS levels can hinder wound healing by exacerbating inflammation and cellular damage” the review, in the journal Pharmaceutics says. Cannabis oil “may help mitigate oxidative damage by scavenging ROS and upregulating antioxidative mechanisms, potentially enhancing wound healing”.
“Cannabis oil, especially its primary bioactive constituents, CBD and THC, demonstrates considerable potential in facilitating skin wound healing by modifying oxidative stress via the regulation of reactive oxygen species” the review states. “Additionally, the antibacterial and analgesic properties of cannabis contribute to reducing the microbial load and minimising the complications associated with chronic wounds” authors added, “thereby enhancing the overall healing efficacy”.
L J University; Saraswati Institute of Pharmaceutical Sciences; Parul University; Ganpat University; L. M. College of Pharmacy; Gujarat University, Gujarat, India. Faculty of Pharmacy, Silpakorn University; Faculty of Pharmacy, Chiang Mai University, Thailand
Fibromyalgia Patients Report Improved Symptoms Following Cannabis Use
April, 2024
Fibromyalgia (FM) patients frequently use cannabis therapeutically and most say it improves their disease symptoms, according to, “A cross-sectional survey study of cannabis use for fibromyalgia symptom management”, published in April 2024 in the journal Mayo Clinic Proceedings. Researchers affiliated with the Mayo Clinic in Minnesota USA (legalised medicinal use in 2015) surveyed 1,336 patients withfibromyalgia.
Half (49.5%) acknowledged using cannabis following their diagnosis. Ninety-nine percent reported using cannabis for pain and 94% reported using it to mitigate stress, anxiety, depression and insomnia. Eighty-two percent said it reduced their FM-related pain and most respondents also rated cannabis as effective in mitigating other disease symptoms.
Authors acknowledged that cannabis use among FM patients is “widespread” and most patients perceive it to have a “favourable impact on pain, stress and sleep disturbances”. Recent observational trial data from Germany and the United Kingdom reports that FM patients typically reduce their use of other prescription medications following their use of cannabis products.
Tetrahydrocannabinol and Cannabidiol for Pain Treatment—An Update on the Evidence
29 January, 2024
Cannabinoids are an attractive pain management option due to their synergistic effects when administered with opioids, thereby also limiting the extent of respiratory depression. On their own, however, cannabinoids have been shown to have the potential to relieve specific subtypes of chronic pain in adults. Among these subtypes are neuropathic, musculoskeletal, cancer and geriatric pain. Another interesting feature is their effectiveness in chemotherapy-induced peripheral neuropathy (CIPN).
Palliative Medicine Clinic, Medical University of Warsaw, Poland.