Medical cannabis alleviates chronic neuropathic pain effectively and sustainably without severe adverse effect - a retrospective study on 99 cases.
These patients received medical cannabis by means of inhaling dried flowers with tetrahydrocannabinol content of <12-22% at a maximal daily dose of 0.15-1 g. Within 6 weeks on the therapy, median of the pain scores decreased significantly from 7.5 to 4.0. The proportion of patients with severe pain (score >6) decreased from 96% to 16%.
Sleep disturbance was significantly improved with the median of the scores decreased from 8.0 to 2.0. These improvements were sustained over a period of up to 6 months. There were no severe adverse events reported. Mild side effects reported were dryness in mucous tissue (5.4%), fatigue (4.8%) and increased appetite (2.7%). Therapy tolerance was reported in 91% of the interviews.
Medical cannabis is safe and highly effective for treating neuropathic pain and concomitant sleep disturbance.
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